Reprogramming somatic cells into pluripotent stem cells mature is one of the top scientific advances of recent years. The generation of iPS cells specific to a patient may have applications in cellular therapy. Three years ago, researchers at the University of Tokyo (Japan) first introduced the technique of transformation of adult cells in other mouse that had the potential of embryonic, 1 thus opening a new alternative to obtaining pluripotent cells without being embryonic stem cells. Later, U.S. researchers obtained human iPS cells for the first time. (more...)

Fanconi Anemia is a common disease hereditary syndromes group of bone marrow failure. The induced pluripotent stem (iPS: Induced pluripotent stem cells) can be obtained in vitro from skin fibroblasts and from other somatic cell division, introducing specific genes or gene products that reprogram the somatic cell nucleus matures. The most common protocols used viral vectors to transfer four specific genes (Oct4, Sox2, Klf4 and c-MYC). Similar to embryonic cells, iPS cells can grow indefinitely in the laboratory and have the ability in vitro to differentiate into several cell lines, including hematopoietic line. (more...)