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Posts Tagged ‘prostate’

A new bare poliserasa

a-new-bare-poliserasa1

Identification of a new serine protease, signed at the Graduate Institute of Oncology, University of Oviedo. The authors cloned a human DNA encoding this new enzyme, named polisher's 2 the second identified human enzyme with several tandem serine protease domains in its amino acid sequence. The article describes its complex organization in domains, also present in the sequences of the two polisher's rat and mouse, and similar to the polisher's 1. The first of three serine protease domain contains all the characteristics of these enzymes, while the second and third lack a key residue, so that it predicts them to be catalytically inactive.

 
The authors make a series of enzyme assays with peptide substrates commonly