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Posts Tagged ‘nuclear’

Nucleation of microtubules in the Golgi

images25Microtubules (MT) can nuclear membranes of the Golgi apparatus (GA). This nucleation requires γ-tubulin complex and γ-Turkish War (γ-tubulin ring complex), a protein recruited by the GA through interactions with proteins GMAP210 and AKAP450. However, microtubules nucleated at the Golgi different from those of the centrosome that are arranged symmetrically, have a preferred growth towards the end of the cell migration and also to be easily acetylated are more stable and are coated with protein-CLASP 2. (more...)
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