Most sporadic colorectal cancers are initiated by activating mutations in the route Want (wingless type), whose products are implicated Eph receptors (Ephraim's) and its ligands.A study on the development of colorectal cancer sample, for the first time that the activity of Eph receptors (responsible for controlling the structure of intestinal epithelium through repulsive interactions with their legends) cancels the progression of benign to malignant tumors. (more...)