Posts Tagged ‘Molecular’

A rare disease characterized by premature aging is modeled after a group of Spanish scientists to better understand the relationship between cancer, genes and aging. This is Werner syndrome, an inherited disorder characterized by premature aging of the individual, genomic instability and an increased incidence of tumors. The study was conducted jointly by researchers at the Hospital Clinic of Barcelona, Biomedical Research Center of Navarre, the National Institute on Aging U.S., and the group of Manel Esteller of the CNIO. Read the rest of this entry »

The gene hedgehog (hh) was initially identified as a key gene in embryonic development of the fruit fly, Drosophila melanogaster. While Drosophila has only one hedgehog gene, vertebrates have three peers. These proteins are secreted extracellular ligands by a group of cells during organ formation in the embryo. In the adult hedgehog maintains and regulates stem cells in many tissues, being instrumental in regenerative processes. There is also a close relation between HH signaling pathway and the development of tumors, genetic alterations observed that stimulate the growth of tumor cells in the digestive tract, lung and prostate .