Molecular Staging Inc. Awarded Two Additional Patents For Rolling Circle Amplification Technology
This further expands the intellectual property estate surrounding MSI’s Rolling Circle Amplification Technology to a total of 11 issued patents, including eight U.S. patents and three international patents.
Rolling Circle Amplification Technology detects and measures proteins as well as nucleic acids with unprecedented sensitivity and expanded multiplexing capabilities.
Patent number 6,287,824 for “Molecular cloning using rolling circle amplification” was issued September 11, 2001. This application of Rolling Circle Amplification Technology enables scientists to clone DNA without using biological host organisms such as bacteria, viruses or yeast cells. The outcome is cloned DNA with far greater coverage than is possible with methods which need to use a biological host. Patent number 6,291,187 for “Polyprimed amplification of nucleic acid sequences,” which was issued September 18, 2001, relates to further enhancements of the significant sensitivity advantages enabled by Rolling Circle Amplification Technology.
In other patent news,
the company was also awarded patent number 6,287,825,
“Methods for reducing the complexity of DNA
sequences,” on September 11, 2001.
This patent adds to the Company’s existing patent
portfolio on Allele Frequency Distortion (AFD), another of
MSI’s proprietary technologies.
MSI is a life science company developing a portfolio of technologies for detection and measurement of proteins and nucleic acids across a broad range of applications, including proteomics, genomics, pharmacogenomics and diagnostics. One of MSI’s core technologies is Rolling Circle Amplification Technology (RCATTM), a proprietary amplification process that has significant advantages in terms of sensitivity, multiplexing, dynamic range and scalability. Additional information about MSI can be found at www.molecularstaging.com