Many disease states require panels of different tests to be conducted simultaneously (multiplexing) to achieve a clinically complete picture. To date, efforts to multiplex tests have been constrained by issues of background noise or interference, or the requirement for extremely sensitive methods of analyte detection. One of the unique features of RCAT is that during the amplification process the signal remains tethered to the analyte of interest. This effectively enables multiplexing capabilities with unprecedented sensitivity and specificity. Current applications of RCAT technology have been developed in a multiplexing format enabling greater than 100 different proteins to be measured simultaneously with significantly greater sensitivity than other current methods. (more...)